STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sodCCu-Zn-superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (186 aa)    
Predicted Functional Partners:
NMB1271
Putative mercury transport periplasmic protein; Identified by similarity to EGAD:28925; match to protein family HMM PF00403.
   
 0.994
sodB
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.888
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
   
 0.828
kat
Catalase; Identified by similarity to EGAD:21555; match to protein family HMM PF00199; Belongs to the catalase family.
  
 0.812
ctrA
Capsule polysaccharide export outer membrane protein CtrA; Involved in transport of capsular polysaccharides to the cell surface. May function as a membrane anchor for capsular polysaccharides. Possible porin properties; Belongs to the BexD/CtrA/VexA family.
      
 0.726
petB
Ubiquinol--cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 
 0.711
NMB0946
Identified by similarity to EGAD:48455; match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM TIGR02190.
   
 
 0.704
NMB0006
Thioredoxin-related protein; Identified by similarity to EGAD:143277.
   
 0.601
NMB1845
Thioredoxin; Identified by similarity to GP:2327006.
   
 0.601
porA
Outer membrane protein PorA; Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
      
 0.600
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.