Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
NMB1435Drug resistance translocase family protein; Identified by similarity to EGAD:20464; match to protein family HMM PF07690. (468 aa)    
Predicted Functional Partners:
farA
Fatty acid efflux system protein; Identified by similarity to EGAD:20365; match to protein family HMM PF00529.
 
 
 0.826
NMB1434
Identified by similarity to EGAD:90768; match to protein family HMM PF00614.
  
    0.514
ybjZ
ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 
 0.508
mtrE
Multidrug efflux pump channel protein; Identified by similarity to EGAD:17129; match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
 
 0.467
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.443
NMB1436
Conserved hypothetical protein; Identified by similarity to EGAD:89510; match to protein family HMM PF02754.
       0.419
NMB1437
Conserved hypothetical protein; Identified by similarity to EGAD:89507; match to protein family HMM PF02589.
       0.419
NMB1438
Conserved hypothetical protein; Identified by similarity to EGAD:89509; match to protein family HMM PF00037; match to protein family HMM TIGR00273.
       0.419
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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