Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB1461Drug resistance translocase family protein; Identified by similarity to EGAD:91169; match to protein family HMM PF07690. (461 aa)    
Predicted Functional Partners:
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
    0.828
NMB1462
Putative transglycosylase; Identified by similarity to EGAD:107330; match to protein family HMM PF01464.
 
    0.641
NMB1081
Bacteriophage transposase; Identified by similarity to EGAD:143678.
   
    0.484
NMB2020
Conserved hypothetical protein; Identified by similarity to EGAD:6204; match to protein family HMM PF01027.
  
     0.464
NMB2099
Conserved hypothetical protein; Identified by similarity to EGAD:33024; match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
   
    0.460
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.443
lptE
Putative rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
   
    0.401
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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