Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB1462Putative transglycosylase; Identified by similarity to EGAD:107330; match to protein family HMM PF01464. (207 aa)    
Predicted Functional Partners:
NMB1461
Drug resistance translocase family protein; Identified by similarity to EGAD:91169; match to protein family HMM PF07690.
 
    0.641
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
     
 0.563
NMB0109
Conserved hypothetical protein; Identified by similarity to EGAD:109565; match to protein family HMM PF01476.
  
     0.541
pilP
pilP protein; Identified by similarity to EGAD:40689; match to protein family HMM PF04351.
  
     0.530
NMB0770
Putative type IV pilus assembly protein PilZ; Identified by similarity to EGAD:38751; match to protein family HMM PF07238.
  
     0.517
ispE
Conserved hypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.516
dsbC
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
      
 0.510
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...]
   
  
 0.507
pilM
pilM protein; Identified by similarity to EGAD:151887; match to protein family HMM TIGR01175.
  
   
 0.490
pilN
pilN protein; Identified by similarity to EGAD:151888; match to protein family HMM PF05137.
  
     0.480
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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