Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lbpBIdentified by similarity to GP:3582728; match to protein family HMM PF01298. (737 aa)    
Predicted Functional Partners:
lbpA
Lactoferrin-binding protein A; Unknown. May be an iron-siderophore receptor.
  
  
 0.971
hmbR
Hemoglobin receptor; Identified by similarity to EGAD:131251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01786.
   
  
 0.796
NMB0572
Hypothetical protein; Identified by Glimmer2; putative.
   
    0.731
fumC
Fumarate hydratase, class II, aerobic; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
    0.731
fbpA
iron(III) ABC transporter, periplasmic binding protein; This protein may be a central component in the iron- acquisition system.
   
  
 0.627
exbD
Biopolymer transport protein ExbD; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
   
  
 0.575
exbB
Biopolymer transport protein ExbB; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
   
  
 0.546
tbp2
Transferrin-binding protein 2; Acts as a transferrin receptor and is required for transferrin utilization.
   
  
0.527
frpB
Iron-regulated outer membrane protein FrpB; Identified by similarity to EGAD:133971; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783.
   
  
 0.493
fbpC
iron(III) ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
   
  
 0.464
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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