Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMB1674GDSL lipase family protein; Identified by similarity to EGAD:18113; match to protein family HMM PF00657. (213 aa)    
Predicted Functional Partners:
tag
DNA-3-methyladenine glycosylase I; Identified by similarity to EGAD:128731; match to protein family HMM PF03352.
  
    0.776
NMB1670
PqiA family protein; Identified by similarity to EGAD:91640; match to protein family HMM PF04403; match to protein family HMM TIGR00155.
  
    0.774
pqiB
pqiB protein; Identified by similarity to EGAD:91619; match to protein family HMM PF02470.
       0.774
NMB1672
Conserved hypothetical protein; Identified by similarity to EGAD:91019; match to protein family HMM PF03886.
       0.774
NMB1669
Iron-starvation protein PigA; Identified by similarity to GP:3091146; match to protein family HMM PF01126.
 
     0.488
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
   
    0.484
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.437
NMB1675
Hypothetical protein; Identified by Glimmer2; putative.
       0.433
cysG-1
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.424
cysG-2
Siroheme synthase; Identified by similarity to EGAD:142433; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470.
     
 0.424
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.