Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ansAIdentified by similarity to EGAD:9104; match to protein family HMM PF00710. (333 aa)    
Predicted Functional Partners:
aspA
Aspartate ammonia-lyase; Identified by similarity to GP:41008; match to protein family HMM PF00206; match to protein family HMM TIGR00839.
  
 
 0.958
argG
Argininosuccinate synthase; Identified by similarity to EGAD:28705; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
   
 
 0.913
aspC
Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.
   
 
 0.902
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
   
 
  0.901
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Identified by similarity to EGAD:124706; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.900
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
     
  0.900
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.900
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.867
lysC
Aspartokinase, alpha and beta subunits; Identified by similarity to EGAD:5784; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
     
 0.814
NMB1687
Conserved hypothetical protein; Identified by similarity to EGAD:17549; match to protein family HMM PF01026.
  
   0.793
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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