Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fixOCytochrome c oxidase, subunit II; Identified by similarity to EGAD:20716; match to protein family HMM PF02433; match to protein family HMM TIGR00781. (203 aa)    
Predicted Functional Partners:
fixP
Cytochrome c oxidase, subunit III; Identified by similarity to EGAD:24821; match to protein family HMM PF00034; match to protein family HMM TIGR00782.
 
 0.999
fixN
Cytochrome c oxidase, subunit I; Identified by similarity to EGAD:125980; match to protein family HMM PF00115; match to protein family HMM TIGR00780; Belongs to the heme-copper respiratory oxidase family.
 0.999
NMB1454
Ferredoxin, 4Fe-4S bacterial type; Identified by similarity to EGAD:40049; match to protein family HMM PF00037.
 
  
 0.981
petA
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.942
petB
Ubiquinol--cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.937
petC
Ubiquinol--cytochrome c reductase, cytochrome c1; Identified by similarity to EGAD:10603; match to protein family HMM PF02167.
   
 0.932
NMB1805
Cytochrome c4; Identified by similarity to EGAD:18580; match to protein family HMM PF00034.
  
 
 0.926
NMB0717
Putative cytochrome; Identified by similarity to EGAD:40915; match to protein family HMM PF00034.
 
 
 0.916
nuoI
NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
   0.742
nuoM
NADH dehydrogenase I, M subunit; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
   
   0.740
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (30%) [HD]