Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilMpilM protein; Identified by similarity to EGAD:151887; match to protein family HMM TIGR01175. (371 aa)    
Predicted Functional Partners:
pilN
pilN protein; Identified by similarity to EGAD:151888; match to protein family HMM PF05137.
 
 
 0.999
pilO
pilO protein; Identified by similarity to GP:1914829; match to protein family HMM PF04350.
 
 
 0.996
pilQ
pilQ protein; Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA (By similarity); Belongs to the bacterial secretin family. PilQ subfamily.
 
 
 0.995
pilP
pilP protein; Identified by similarity to EGAD:40689; match to protein family HMM PF04351.
 
  
 0.990
pilF
Type IV pilus assembly protein; Identified by similarity to EGAD:21691; match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538.
 
 
 0.931
pilG
Pilus assembly protein PilG; Identified by similarity to EGAD:40687; match to protein family HMM PF00482.
 
 
 
 0.912
pilD
Type IV prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.893
NMB0109
Conserved hypothetical protein; Identified by similarity to EGAD:109565; match to protein family HMM PF01476.
  
 
   0.873
NMB1309
Putative fimbrial biogenesis and twitching motility protein; Identified by similarity to EGAD:39885; match to protein family HMM PF00515; match to protein family HMM TIGR02521.
  
   
 0.845
fimT
Fimbrial protein FimT; Identified by similarity to SP:P13253; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
 
   
 0.826
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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