Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdaBModulator of drug activity B; Identified by similarity to EGAD:90558; match to protein family HMM PF02525. (192 aa)    
Predicted Functional Partners:
kefB
Glutathione-regulated potassium-efflux system protein; Identified by similarity to EGAD:29394; match to protein family HMM PF02080; match to protein family HMM PF02254; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.898
NMB1856
Transcriptional regulator, LysR family; Identified by similarity to EGAD:15923; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
 
   
 0.864
NMB0508
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.696
cysT
Sulfate ABC transporter, permease protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
      
 0.696
cysB
Cys regulon transcriptional activator; Identified by similarity to EGAD:32791; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
      
 0.670
NMB2140
Conserved hypothetical protein; Identified by similarity to EGAD:28593; match to protein family HMM PF07681.
  
  
 0.653
NMB0120
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.510
cysW
Sulfate ABC transporter, permease protein; Identified by similarity to EGAD:49750; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140.
      
 0.510
ptsH
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
      
 0.510
NMB1638
Identified by similarity to EGAD:20220; match to protein family HMM PF00884; match to protein family HMM PF08019.
  
     0.476
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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