Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMB1946Outer membrane lipoprotein; Identified by similarity to EGAD:30554; match to protein family HMM PF03180; Belongs to the nlpA lipoprotein family. (287 aa)    
Predicted Functional Partners:
NMB1947
ABC transporter, permease protein; Identified by similarity to GP:303561; match to protein family HMM PF00528.
 0.999
NMB1948
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
 
 0.997
frpC
Iron-regulated protein FrpC; May participate in the pathogenesis of meningococcal disease.
      
 0.510
NMB0938
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.508
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.508
NMB0586
Putative adhesin; Identified by similarity to EGAD:16475; match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
      
 0.442
NMB1483
Putative lipoprotein NlpD; Identified by similarity to EGAD:20336; match to protein family HMM PF01476; match to protein family HMM PF01551.
      
 0.438
NMB0299
comEA-related protein; Identified by similarity to EGAD:36757; match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259.
      
 0.420
NMB0039
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.405
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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