STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NMB1979Conserved hypothetical protein; Identified by similarity to EGAD:28633; match to protein family HMM PF03601; match to protein family HMM TIGR00698. (338 aa)    
Predicted Functional Partners:
NMB1980
Conserved hypothetical protein; Identified by similarity to EGAD:29414.
       0.689
cyaY
cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
  
    0.686
rlpA
Conserved hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
      
 0.677
NMB0432
Conserved hypothetical protein; Identified by similarity to EGAD:24560; match to protein family HMM PF01925.
     
 0.673
luxS
Conserved hypothetical protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
    0.633
dedA
dedA protein; Identified by similarity to EGAD:14096; match to protein family HMM PF00597.
      
 0.574
NMB0436
Conserved hypothetical protein; Identified by similarity to EGAD:28201; match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family.
      
 0.510
NMB1977
Hypothetical protein; Identified by Glimmer2; putative.
       0.497
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.493
NMB0434
Putative AcnD-accessory protein PrpF; Identified by similarity to EGAD:91576; match to protein family HMM PF04303; match to protein family HMM TIGR02334.
      
 0.430
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.