hap protein (Neisseria meningitidis) - STRING interaction network

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hap

Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414. (1457 aa)

Predicted Functional Partners:

hsf

0.774

nadA

0.704

opc

0.670

NMB1108

0.627

NMB1986

0.612

polA

0.497

NMB1969

0.454

nagZ

0.445

rpoB

0.436

NMB0067

0.420

Your Current Organism:

Neisseria meningitidis

NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NMB0067	hap	NMB0067	NMB1985	Polysialic acid capsule biosynthesis protein SiaD, truncation; Identified by similarity to GP:530041.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.420
NMB1108	hap	NMB1108	NMB1985	Hypothetical protein; Identified by Glimmer2; putative.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.627
NMB1969	hap	NMB1969	NMB1985	Putative serotype-1-specific antigen; Identified by similarity to EGAD:23198; match to protein family HMM PF00082; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.454
NMB1986	hap	NMB1986	NMB1985	Hypothetical protein; Identified by Glimmer2; putative.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.612
NMB1986	hsf	NMB1986	NMB0992	Hypothetical protein; Identified by Glimmer2; putative.	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	0.422
hap	NMB0067	NMB1985	NMB0067	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Polysialic acid capsule biosynthesis protein SiaD, truncation; Identified by similarity to GP:530041.	0.420
hap	NMB1108	NMB1985	NMB1108	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Hypothetical protein; Identified by Glimmer2; putative.	0.627
hap	NMB1969	NMB1985	NMB1969	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Putative serotype-1-specific antigen; Identified by similarity to EGAD:23198; match to protein family HMM PF00082; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.454
hap	NMB1986	NMB1985	NMB1986	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Hypothetical protein; Identified by Glimmer2; putative.	0.612
hap	hsf	NMB1985	NMB0992	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	0.774
hap	nadA	NMB1985	NMB0394	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.	0.704
hap	nagZ	NMB1985	NMB0530	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Glycosyl hydrolase, family 3; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.445
hap	opc	NMB1985	NMB1053	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.	0.670
hap	polA	NMB1985	NMB1982	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.497
hap	rpoB	NMB1985	NMB0132	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.436
hsf	NMB1986	NMB0992	NMB1986	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	Hypothetical protein; Identified by Glimmer2; putative.	0.422
hsf	hap	NMB0992	NMB1985	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.774
hsf	nadA	NMB0992	NMB0394	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.	0.785
hsf	opc	NMB0992	NMB1053	Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.	Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.	0.774
nadA	hap	NMB0394	NMB1985	Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.	Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.	0.704

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