STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hapAdhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414. (1457 aa)    
Predicted Functional Partners:
hsf
Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.
   
  
 0.727
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
  
  
 0.644
NMB1986
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.612
opc
Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.
      
 0.539
NMB1969
Putative serotype-1-specific antigen; Identified by similarity to EGAD:23198; match to protein family HMM PF00082; match to protein family HMM PF03797; match to protein family HMM TIGR01414.
  
  
 0.476
rmpM
Outer membrane protein class 4; Identified by similarity to EGAD:10394; match to protein family HMM PF00691.
  
  
 0.467
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.460
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.450
NMB0345
Putative cell-binding factor; Identified by similarity to EGAD:12394.
   
 
 0.419
comA
Competence protein ComA; Identified by similarity to EGAD:32733; match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361.
   
  
 0.416
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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