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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (252 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
  
 0.993
NMB2049
Glyoxalase II family protein; Identified by similarity to EGAD:91564; match to protein family HMM PF00753.
  
 
  0.922
ldhA
D-lactate dehydrogenase; Identified by similarity to EGAD:28739; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.907
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
     
 0.900
NMB1970
Putative para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase; Identified by similarity to EGAD:90483; match to protein family HMM PF00425.
  
  
 0.740
mgtE
Magnesium transporter; Acts as a magnesium transporter.
  
  
 0.651
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
    0.609
NMB0773
Conserved hypothetical protein; Identified by similarity to EGAD:50035; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
  
  
 0.602
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.530
kefB
Glutathione-regulated potassium-efflux system protein; Identified by similarity to EGAD:29394; match to protein family HMM PF02080; match to protein family HMM PF02254; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.499
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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