Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (252 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
 0.993
NMB2049
Glyoxalase II family protein; Identified by similarity to EGAD:91564; match to protein family HMM PF00753.
  
 
 0.926
ldhA
D-lactate dehydrogenase; Identified by similarity to EGAD:28739; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
  0.906
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
     
  0.900
NMB1970
Putative para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase; Identified by similarity to EGAD:90483; match to protein family HMM PF00425.
  
  
 0.775
mraZ
Conserved hypothetical protein; Identified by similarity to EGAD:6617; match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family.
  
   
 0.625
mgtE
Magnesium transporter; Acts as a magnesium transporter.
  
  
 0.616
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
    0.610
NMB0773
Conserved hypothetical protein; Identified by similarity to EGAD:50035; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
  
  
 0.608
gshB
Glutathione synthetase; Identified by similarity to EGAD:6965; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380.
 
   
 0.542
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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