Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kdtBLipopolysaccharide core biosynthesis protein KdtB; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)    
Predicted Functional Partners:
coaBC
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.982
coaE
Putative kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.966
birA/coaX
BirA protein/Bvg accessory factor; Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins; In the C-terminal section; belongs to the type III pantothenate kinase family.
    
 0.948
folC
Folylpolyglutamate synthase/dihydrofolate synthase; Identified by similarity to EGAD:40703; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
  
   
 0.799
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 
 0.790
NMB0122
Conserved hypothetical protein; Identified by similarity to EGAD:7463; match to protein family HMM PF03602; match to protein family HMM TIGR00095.
 
  
 0.788
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
      
 0.758
NMB2018
Conserved hypothetical protein; Identified by similarity to EGAD:27877; match to protein family HMM PF00849; match to protein family HMM TIGR01621.
  
    0.707
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
   
  
 0.686
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.669
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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