STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
porBMajor outer membrane protein PIB; Serves as a slightly cation selective porin; Belongs to the Gram-negative porin family. (331 aa)    
Predicted Functional Partners:
rmpM
Outer membrane protein class 4; Identified by similarity to EGAD:10394; match to protein family HMM PF00691.
  
 0.954
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
   
  
 0.820
opc
Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.
      
 0.809
nspA
Outer membrane protein NspA; Identified by similarity to EGAD:137514; match to protein family HMM PF02462.
   
 
 0.796
porA
Outer membrane protein PorA; Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
  
 
0.769
NMB1954
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.749
omp85
Outer membrane protein Omp85; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
  
 
 0.745
penA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
   
  
 0.728
pilQ
pilQ protein; Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA (By similarity); Belongs to the bacterial secretin family. PilQ subfamily.
      
 0.726
tbp2
Transferrin-binding protein 2; Acts as a transferrin receptor and is required for transferrin utilization.
   
  
 0.725
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.