Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gpsAGlycerol-3-phosphate dehydrogenase (NAD+); Identified by similarity to EGAD:8708; match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa)    
Predicted Functional Partners:
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
 0.984
der
Essential GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
 0.941
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
    
 0.828
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
     
 0.828
NMB2034
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by similarity to EGAD:162666; match to protein family HMM PF01553.
    
 0.828
plsX
Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.708
NMB2157
Putative pyrazinamidase/nicotinamidase PncA; Identified by similarity to EGAD:140533; match to protein family HMM PF00857.
  
   0.665
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.636
NMB2058
Conserved hypothetical protein; Identified by similarity to EGAD:29842; match to protein family HMM PF05164.
       0.621
NMB2059
Hypothetical protein; Identified by Glimmer2; putative.
       0.614
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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