Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
autAut protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (168 aa)    
Predicted Functional Partners:
gmhB
Putative histidinol-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. Belongs to the GmhB family.
  
 0.996
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
   
 0.986
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
 
  
 0.981
NMB0825
Putative ADP-heptose synthase; Identified by similarity to GP:1017464; match to protein family HMM PF00294; match to protein family HMM TIGR02198.
   
 0.979
rfaC
Identified by similarity to EGAD:40648; match to protein family HMM PF01075; match to protein family HMM TIGR02193.
 
   
 0.882
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
      0.827
birA/coaX
BirA protein/Bvg accessory factor; Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins; In the C-terminal section; belongs to the type III pantothenate kinase family.
       0.813
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
   
  
 0.779
NMB2098
Conserved hypothetical protein; Identified by similarity to GP:2897873.
      
 0.774
rfaF
ADP-heptose--LPS heptosyltransferase II; Identified by similarity to EGAD:40767; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
 
   
 0.768
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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