Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB2091Putative hemolysin; Identified by similarity to EGAD:28637; match to protein family HMM PF04972. (202 aa)    
Predicted Functional Partners:
NMB2092
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
  
    0.748
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; Identified by similarity to GP:3273344.
  
     0.710
NMB2089
Conserved hypothetical protein; Identified by similarity to EGAD:89286; match to protein family HMM PF02021; match to protein family HMM TIGR00252; Belongs to the UPF0102 family.
       0.657
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.642
priB
Putative primosomal replication protein n; Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded DNA-binding by PriB. Activates DNA-dependent ATP hydrolysis catalyzed by PriA.
  
     0.543
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to GP:3273343; match to protein family HMM PF01127.
  
     0.537
NMB0928
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.512
mlp
Lipoprotein; Identified by similarity to EGAD:40759; match to protein family HMM PF04355.
  
  
 0.492
NMB2020
Conserved hypothetical protein; Identified by similarity to EGAD:6204; match to protein family HMM PF01027.
  
    0.484
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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