Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yojHMalate:quinone oxidoreductase; Identified by similarity to EGAD:9906; match to protein family HMM PF06039; match to protein family HMM TIGR01320. (488 aa)    
Predicted Functional Partners:
fumB
Fumarate hydratase, class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.956
pprC
Methylcitrate synthase/citrate synthase 2; Identified by similarity to EGAD:90798; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
   
 
 0.954
gltA
Citrate synthase; Identified by similarity to EGAD:12765; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
   
 
 0.947
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.946
fumC
Fumarate hydratase, class II, aerobic; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.944
sfcA
Malate oxidoreductase (NAD); Identified by similarity to GP:1799887; match to protein family HMM PF00390; match to protein family HMM PF03949.
  
 
 0.919
argH
Argininosuccinate lyase; Identified by similarity to EGAD:49512; match to protein family HMM PF00206; match to protein family HMM TIGR00838.
    
 0.835
NMB1353
Identified by similarity to EGAD:91347; match to protein family HMM PF00171.
   
 
 0.812
gabD
Succinate-semialdehyde dehydrogenase (NADP+); Identified by similarity to EGAD:16804; match to protein family HMM PF00171; match to protein family HMM TIGR01780; Belongs to the aldehyde dehydrogenase family.
   
 
 0.812
purB
Adenylosuccinate lyase; Identified by similarity to EGAD:14517; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.800
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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