SFQ56942.1 protein (Siccationidurans arizonensis)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

SFQ56942.1

Heme exporter protein B. (233 aa)

Predicted Functional Partners:

SFQ56928.1

0.999

SFP92022.1

0.995

SFQ56901.1

0.959

SFQ56914.1

0.913

SFQ56865.1

0.896

SFQ56960.1

0.828

SFQ57085.1

0.768

SFQ39854.1

0.743

SFP77130.1

0.712

SFQ03302.1

0.709

Your Current Organism:

Siccationidurans arizonensis

NCBI taxonomy Id: 1227077
Other names: DSM 17870, Hymenobacter arizonensis, Hymenobacter arizonensis Reddy and Garcia-Pichel 2013, Hymenobacter sp. OR362-8, JCM 13504, S. arizonensis, strain OR362-8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFP77130.1	SFQ03302.1	SAMN04515668_0287	SAMN04515668_1225	Hypothetical protein.	Hypothetical protein.	0.415
SFP77130.1	SFQ39854.1	SAMN04515668_0287	SAMN04515668_2265	Hypothetical protein.	Hypothetical protein.	0.529
SFP77130.1	SFQ56865.1	SAMN04515668_0287	SAMN04515668_2983	Hypothetical protein.	Cytochrome c-type biogenesis protein CcmF.	0.602
SFP77130.1	SFQ56901.1	SAMN04515668_0287	SAMN04515668_2985	Hypothetical protein.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.	0.731
SFP77130.1	SFQ56914.1	SAMN04515668_0287	SAMN04515668_2986	Hypothetical protein.	Hypothetical protein.	0.472
SFP77130.1	SFQ56928.1	SAMN04515668_0287	SAMN04515668_2987	Hypothetical protein.	Heme exporter protein C.	0.487
SFP77130.1	SFQ56942.1	SAMN04515668_0287	SAMN04515668_2988	Hypothetical protein.	Heme exporter protein B.	0.712
SFP77130.1	SFQ57085.1	SAMN04515668_0287	SAMN04515668_2997	Hypothetical protein.	CarboxypepD_reg-like domain-containing protein.	0.480
SFP92022.1	SFQ39854.1	SAMN04515668_0829	SAMN04515668_2265	ABC transporter.	Hypothetical protein.	0.593
SFP92022.1	SFQ56865.1	SAMN04515668_0829	SAMN04515668_2983	ABC transporter.	Cytochrome c-type biogenesis protein CcmF.	0.602
SFP92022.1	SFQ56901.1	SAMN04515668_0829	SAMN04515668_2985	ABC transporter.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.	0.830
SFP92022.1	SFQ56914.1	SAMN04515668_0829	SAMN04515668_2986	ABC transporter.	Hypothetical protein.	0.493
SFP92022.1	SFQ56928.1	SAMN04515668_0829	SAMN04515668_2987	ABC transporter.	Heme exporter protein C.	0.989
SFP92022.1	SFQ56942.1	SAMN04515668_0829	SAMN04515668_2988	ABC transporter.	Heme exporter protein B.	0.995
SFP92022.1	SFQ57085.1	SAMN04515668_0829	SAMN04515668_2997	ABC transporter.	CarboxypepD_reg-like domain-containing protein.	0.583
SFQ03302.1	SFP77130.1	SAMN04515668_1225	SAMN04515668_0287	Hypothetical protein.	Hypothetical protein.	0.415
SFQ03302.1	SFQ56865.1	SAMN04515668_1225	SAMN04515668_2983	Hypothetical protein.	Cytochrome c-type biogenesis protein CcmF.	0.667
SFQ03302.1	SFQ56901.1	SAMN04515668_1225	SAMN04515668_2985	Hypothetical protein.	Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.	0.662
SFQ03302.1	SFQ56914.1	SAMN04515668_1225	SAMN04515668_2986	Hypothetical protein.	Hypothetical protein.	0.438
SFQ03302.1	SFQ56942.1	SAMN04515668_1225	SAMN04515668_2988	Hypothetical protein.	Heme exporter protein B.	0.709

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.841

expected number of edges:

15

PPI enrichment p-value:

0.103

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005975

Carbohydrate metabolic process

9 of 207

1.14

1.4

6.82e-07

GO:0005976

Polysaccharide metabolic process

5 of 57

1.45

1.36

0.00040

GO:0009225

Nucleotide-sugar metabolic process

3 of 18

1.73

1.08

0.0064

GO:0034637

Cellular carbohydrate biosynthetic process

4 of 46

1.44

1.06

0.0036

GO:0016051

Carbohydrate biosynthetic process

5 of 90

1.25

0.99

0.0023

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016779

Nucleotidyltransferase activity

5 of 51

1.5

1.45

0.00026

GO:0016868

Intramolecular transferase activity, phosphotransferases

2 of 5

2.11

0.73

0.0446

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2438

O-Antigen nucleotide sugar biosynthesis, and Alpha-D-phosphohexomutase, C-terminal

5 of 16

2.0

2.98

3.33e-07

CL:2431

Mixed, incl. Polysaccharide metabolic process, and O-Antigen nucleotide sugar biosynthesis

9 of 83

1.54

2.83

1.64e-10

CL:2439

O-Antigen nucleotide sugar biosynthesis

4 of 8

2.2

2.8

2.57e-06

CL:2434

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

6 of 50

1.58

2.25

7.27e-07

CL:2565

Glucan metabolic process, and Disaccharide metabolic process

3 of 10

1.98

1.68

0.00043

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00541

O-Antigen nucleotide sugar biosynthesis

6 of 22

1.94

3.56

4.04e-09

map00520

Amino sugar and nucleotide sugar metabolism

8 of 52

1.69

3.36

8.78e-11

map00500

Starch and sucrose metabolism

6 of 33

1.76

2.98

2.30e-08

map00052

Galactose metabolism

3 of 22

1.64

1.32

0.0013

map00521

Streptomycin biosynthesis

2 of 17

1.57

0.77

0.0265

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0548

Nucleotidyltransferase

4 of 42

1.48

1.19

0.0017

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12804

MobA-like NTP transferase domain

4 of 9

2.15

2.36

2.07e-05

PF02880

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III

2 of 3

2.33

0.87

0.0251

PF02879

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II

2 of 3

2.33

0.87

0.0251

PF02878

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I

2 of 3

2.33

0.87

0.0251

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005835

Nucleotidyl transferase domain

4 of 6

2.33

2.65

7.64e-06

IPR029044

Nucleotide-diphospho-sugar transferases

6 of 37

1.71

2.38

1.45e-06

IPR036900

Alpha-D-phosphohexomutase, C-terminal domain superfamily

2 of 3

2.33

0.75

0.0419

IPR016066

Alpha-D-phosphohexomutase, conserved site

2 of 3

2.33

0.75

0.0419

IPR016055

Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

2 of 3

2.33

0.75

0.0419

(more ...)

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