| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERH16816.1 | ERH19897.1 | HMPREF0043_01701 | HMPREF0043_00264 | Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.915 |
| ERH16816.1 | glyA | HMPREF0043_01701 | HMPREF0043_01682 | Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.478 |
| ERH18784.1 | ERH19409.1 | HMPREF0043_01174 | HMPREF0043_00717 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | 0.932 |
| ERH18784.1 | ERH19897.1 | HMPREF0043_01174 | HMPREF0043_00264 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.882 |
| ERH18784.1 | ERH19898.1 | HMPREF0043_01174 | HMPREF0043_00265 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: iva:Isova_1082 2.8e-117 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.881 |
| ERH18784.1 | ERH20140.1 | HMPREF0043_01174 | HMPREF0043_00122 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | KEGG: ske:Sked_33270 2.0e-139 L-serine ammonia-lyase; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 7.50. | 0.886 |
| ERH18784.1 | cysS | HMPREF0043_01174 | HMPREF0043_01328 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | cysteine--tRNA ligase; KEGG: ahe:Arch_1659 1.8e-177 cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.442 |
| ERH18784.1 | glyA | HMPREF0043_01174 | HMPREF0043_01682 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.543 |
| ERH18784.1 | thrB | HMPREF0043_01174 | HMPREF0043_01172 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
| ERH18784.1 | trpA | HMPREF0043_01174 | HMPREF0043_00403 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.551 |
| ERH18784.1 | trpB | HMPREF0043_01174 | HMPREF0043_00404 | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.467 |
| ERH19409.1 | ERH18784.1 | HMPREF0043_00717 | HMPREF0043_01174 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.932 |
| ERH19409.1 | ERH19897.1 | HMPREF0043_00717 | HMPREF0043_00264 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.919 |
| ERH19409.1 | ERH19898.1 | HMPREF0043_00717 | HMPREF0043_00265 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | KEGG: iva:Isova_1082 2.8e-117 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.994 |
| ERH19409.1 | ERH20140.1 | HMPREF0043_00717 | HMPREF0043_00122 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | KEGG: ske:Sked_33270 2.0e-139 L-serine ammonia-lyase; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 7.50. | 0.851 |
| ERH19409.1 | cysS | HMPREF0043_00717 | HMPREF0043_01328 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | cysteine--tRNA ligase; KEGG: ahe:Arch_1659 1.8e-177 cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.501 |
| ERH19409.1 | glyA | HMPREF0043_00717 | HMPREF0043_01682 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.443 |
| ERH19409.1 | thrB | HMPREF0043_00717 | HMPREF0043_01172 | Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.908 |
| ERH19897.1 | ERH16816.1 | HMPREF0043_00264 | HMPREF0043_01701 | KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.915 |
| ERH19897.1 | ERH18784.1 | HMPREF0043_00264 | HMPREF0043_01174 | KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: bcv:Bcav_1281 6.3e-127 Homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 7.50. | 0.882 |