STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH19898.1KEGG: iva:Isova_1082 2.8e-117 cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)    
Predicted Functional Partners:
ERH19897.1
KEGG: cga:Celgi_2187 2.1e-64 serine O-acetyltransferase; K00640 serine O-acetyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
ERH19409.1
Cys/Met metabolism PLP-dependent enzyme; KEGG: bcv:Bcav_1594 4.3e-121 cystathionine gamma-lyase K01739; Psort location: Cytoplasmic, score: 9.97.
  
 0.994
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.922
ERH16280.1
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.921
ERH19430.1
Aminotransferase, class I/II; KEGG: gob:Gobs_1786 2.9e-74 class I and II aminotransferase protein; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 7.50.
    
 0.916
ERH14740.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: kra:Krad_0513 4.3e-144 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.914
ERH16606.1
Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.912
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.910
ERH19241.1
Putative aspartate transaminase; KEGG: ahe:Arch_1404 1.4e-156 class I and II aminotransferase; Psort location: Cytoplasmic, score: 7.50.
   
 0.906
cysS
cysteine--tRNA ligase; KEGG: ahe:Arch_1659 1.8e-177 cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.906
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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