| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERH16700.1 | ERH18958.1 | HMPREF0043_01775 | HMPREF0043_01005 | Hydrolase, NUDIX family; KEGG: bfa:Bfae_11390 3.3e-50 Zn-finger containing NTP pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family. | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.875 |
| ERH16700.1 | ERH19358.1 | HMPREF0043_01775 | HMPREF0043_00765 | Hydrolase, NUDIX family; KEGG: bfa:Bfae_11390 3.3e-50 Zn-finger containing NTP pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.895 |
| ERH16700.1 | nadD | HMPREF0043_01775 | HMPREF0043_00688 | Hydrolase, NUDIX family; KEGG: bfa:Bfae_11390 3.3e-50 Zn-finger containing NTP pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.876 |
| ERH16700.1 | nadE | HMPREF0043_01775 | HMPREF0043_01386 | Hydrolase, NUDIX family; KEGG: bfa:Bfae_11390 3.3e-50 Zn-finger containing NTP pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.940 |
| ERH17079.1 | ERH17081.1 | HMPREF0043_01535 | HMPREF0043_01537 | KEGG: ccm:Ccan_14080 1.6e-21 capsule biosynthesis protein capA K07282; Psort location: CytoplasmicMembrane, score: 8.78. | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | 0.580 |
| ERH17079.1 | ERH19358.1 | HMPREF0043_01535 | HMPREF0043_00765 | KEGG: ccm:Ccan_14080 1.6e-21 capsule biosynthesis protein capA K07282; Psort location: CytoplasmicMembrane, score: 8.78. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.728 |
| ERH17081.1 | ERH17079.1 | HMPREF0043_01537 | HMPREF0043_01535 | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | KEGG: ccm:Ccan_14080 1.6e-21 capsule biosynthesis protein capA K07282; Psort location: CytoplasmicMembrane, score: 8.78. | 0.580 |
| ERH17081.1 | ERH18958.1 | HMPREF0043_01537 | HMPREF0043_01005 | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.870 |
| ERH17081.1 | ERH19358.1 | HMPREF0043_01537 | HMPREF0043_00765 | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.913 |
| ERH17081.1 | nadD | HMPREF0043_01537 | HMPREF0043_00688 | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.926 |
| ERH17081.1 | nadE | HMPREF0043_01537 | HMPREF0043_01386 | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.919 |
| ERH17645.1 | ERH18958.1 | HMPREF0043_01351 | HMPREF0043_01005 | KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.843 |
| ERH17645.1 | ERH19358.1 | HMPREF0043_01351 | HMPREF0043_00765 | KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.852 |
| ERH17645.1 | nadD | HMPREF0043_01351 | HMPREF0043_00688 | KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.863 |
| ERH17645.1 | nadE | HMPREF0043_01351 | HMPREF0043_01386 | KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.644 |
| ERH18958.1 | ERH16700.1 | HMPREF0043_01005 | HMPREF0043_01775 | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Hydrolase, NUDIX family; KEGG: bfa:Bfae_11390 3.3e-50 Zn-finger containing NTP pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family. | 0.875 |
| ERH18958.1 | ERH17081.1 | HMPREF0043_01005 | HMPREF0043_01537 | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.8e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family. | 0.870 |
| ERH18958.1 | ERH17645.1 | HMPREF0043_01005 | HMPREF0043_01351 | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. | 0.843 |
| ERH18958.1 | ERH19358.1 | HMPREF0043_01005 | HMPREF0043_00765 | 5'-nucleotidase protein; KEGG: cgt:cgR_0412 2.4e-95 hypothetical protein; K01081 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.867 |
| ERH18995.1 | ERH19358.1 | HMPREF0043_01042 | HMPREF0043_00765 | Isochorismatase family protein; KEGG: mcu:HMPREF0573_10449 3.6e-76 pncA; putative nicotinamidase K08281; Psort location: Cytoplasmic, score: 9.97. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.991 |