STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaAPantothenate kinase; KEGG: cfi:Celf_1046 6.3e-104 pantothenate kinase; K00867 type I pantothenate kinase; Psort location: Cytoplasmic, score: 7.50. (313 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.961
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.941
ERH19870.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
   
 
 0.909
ERH18713.1
Phosphopantothenoylcysteine decarboxylase domain protein; KEGG: rcu:RCOM_1847870 2.2e-15 phosphopentothenoylcysteine decarboxylase, putative; Psort location: CytoplasmicMembrane, score: 9.55.
   
 
 0.827
ERH18742.1
NADP oxidoreductase coenzyme F420-dependent; KEGG: bcv:Bcav_0716 4.7e-83 pantoate/beta-alanine ligase.
     
 0.785
nnrD
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
    0.688
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
       0.670
ERH19204.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.656
ERH19205.1
Hydrolase, P-loop family; KEGG: cmi:CMM_2573 8.2e-32 alrA2; putative alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50.
       0.656
ERH19207.1
Universal bacterial protein YeaZ; KEGG: xce:Xcel_0675 4.8e-26 peptidase M22 glycoprotease; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 7.50.
       0.656
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.