STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH19069.1KEGG: cfi:Celf_0243 1.1e-168 adenylosuccinate lyase; K01756 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 7.50. (472 aa)    
Predicted Functional Partners:
purC
KEGG: bcv:Bcav_3594 3.3e-91 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50; Belongs to the SAICAR synthetase family.
  
 0.997
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.997
purH
KEGG: gob:Gobs_4419 7.3e-181 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 0.995
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.974
purD
KEGG: cfi:Celf_3231 5.9e-140 phosphoribosylamine/glycine ligase K01945; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family.
  
 0.967
apt
Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.967
ERH14727.1
MaoC-like protein; KEGG: cva:CVAR_2516 0. fas; fatty acid synthase K11533; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.961
ERH14207.1
Beta-ketoacyl synthase protein; KEGG: cva:CVAR_2516 0. fas; fatty acid synthase K11533; Psort location: CytoplasmicMembrane, score: 8.78.
  
 
 0.961
ERH17526.1
KEGG: ase:ACPL_896 3.8e-58 purN; phosphoribosylglycinamide formyltransferase K11175; Psort location: Cytoplasmic, score: 7.50.
  
 0.935
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.934
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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