STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speESpermine/spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (508 aa)    
Predicted Functional Partners:
ERH18941.1
Putative S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
 
  
  0.992
ERH15046.1
Hypothetical protein; KEGG: rha:RHA1_ro02466 7.6e-44 spermidine synthase K00797; Psort location: Cytoplasmic, score: 7.50.
    
  0.849
ERH18939.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.798
ERH20179.1
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase domain protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.787
ERH20136.1
Hypothetical protein; KEGG: ahe:Arch_0113 2.6e-08 MTA/SAH nucleosidase; Psort location: CytoplasmicMembrane, score: 9.55.
     
 0.787
ERH18940.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.716
ERH18983.1
Amine oxidase; KEGG: bps:BPSS1278 4.3e-50 oxidoreductase; K00231 oxygen-dependent protoporphyrinogen oxidase; Psort location: CytoplasmicMembrane, score: 8.16.
    
  0.483
ERH18942.1
Hypothetical protein.
       0.464
ERH16918.1
Hypothetical protein; KEGG: rop:ROP_50160 2.1e-32 acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
   
 
  0.434
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.