| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERH17534.1 | ERH17798.1 | HMPREF0043_01434 | HMPREF0043_01324 | KEGG: mhd:Marky_2217 1.4e-74 NADPH dehydrogenase; Psort location: Cytoplasmic, score: 7.50. | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 0.544 |
| ERH17797.1 | ERH17798.1 | HMPREF0043_01323 | HMPREF0043_01324 | Hypothetical protein. | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 0.547 |
| ERH17797.1 | ispD | HMPREF0043_01323 | HMPREF0043_01325 | Hypothetical protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.546 |
| ERH17798.1 | ERH17534.1 | HMPREF0043_01324 | HMPREF0043_01434 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | KEGG: mhd:Marky_2217 1.4e-74 NADPH dehydrogenase; Psort location: Cytoplasmic, score: 7.50. | 0.544 |
| ERH17798.1 | ERH17797.1 | HMPREF0043_01324 | HMPREF0043_01323 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein. | 0.547 |
| ERH17798.1 | ispD | HMPREF0043_01324 | HMPREF0043_01325 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.956 |
| ERH17798.1 | ispF | HMPREF0043_01324 | HMPREF0043_01326 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.579 |
| ERH17798.1 | rbpA | HMPREF0043_01324 | HMPREF0043_00354 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | 0.999 |
| ERH17798.1 | rpoA | HMPREF0043_01324 | HMPREF0043_00869 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| ERH17798.1 | rpoB | HMPREF0043_01324 | HMPREF0043_00822 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| ERH17798.1 | rpoC | HMPREF0043_01324 | HMPREF0043_00823 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| ERH17798.1 | rpoZ | HMPREF0043_01324 | HMPREF0043_00333 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.999 |
| ERH17798.1 | sigA | HMPREF0043_01324 | HMPREF0043_01819 | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.999 |
| ispD | ERH17797.1 | HMPREF0043_01325 | HMPREF0043_01323 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | Hypothetical protein. | 0.546 |
| ispD | ERH17798.1 | HMPREF0043_01325 | HMPREF0043_01324 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 0.956 |
| ispD | ispF | HMPREF0043_01325 | HMPREF0043_01326 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.999 |
| ispF | ERH17798.1 | HMPREF0043_01326 | HMPREF0043_01324 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 0.579 |
| ispF | ispD | HMPREF0043_01326 | HMPREF0043_01325 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.999 |
| rbpA | ERH17798.1 | HMPREF0043_00354 | HMPREF0043_01324 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | CarD-like protein; KEGG: apb:SAR116_1070 1.1e-19 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| rbpA | rpoA | HMPREF0043_00354 | HMPREF0043_00869 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |