STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH17645.1KEGG: ahe:Arch_1331 0. succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239; Psort location: Cytoplasmic, score: 9.89. (652 aa)    
Predicted Functional Partners:
ERH17644.1
KEGG: mph:MLP_16550 9.3e-39 sdhC; succinate dehydrogenase cytochrome b subunit K00241; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.999
ERH17646.1
KEGG: ahe:Arch_1330 4.3e-112 succinate dehydrogenase and fumarate reductase iron-sulfur protein; K00240 succinate dehydrogenase iron-sulfur subunit; Psort location: Cytoplasmic, score: 9.89.
 
 0.999
ERH18794.1
KEGG: ahe:Arch_0346 0. 2-oxoglutarate dehydrogenase, E1 subunit; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97.
  
 0.997
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.984
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.984
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.979
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.949
ERH14871.1
Putative ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 0.935
ERH17521.1
Aldehyde dehydrogenase family protein; KEGG: aau:AAur_0671 0. proline dehydrogenase; K13821 proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the aldehyde dehydrogenase family.
   
 0.913
ERH15174.1
NADH oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
  
 
 0.903
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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