STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (419 aa)    
Predicted Functional Partners:
ERH17342.1
Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
 
     0.944
ERH19711.1
Glutamyl-queuosine tRNA(Asp) synthetase; KEGG: ahe:Arch_0178 1.5e-84 glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain protein; K01885 glutamyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.787
ERH19770.1
Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: bcv:Bcav_2236 5.0e-40 FKBP-type peptidylprolyl isomerase; K01802 peptidylprolyl isomerase; Psort location: CytoplasmicMembrane, score: 9.55.
    
  0.596
ERH19525.1
Putative FK506-binding protein; KEGG: ahe:Arch_1507 5.8e-46 FKBP-type peptidylprolyl isomerase; K01802 peptidylprolyl isomerase; Psort location: Cytoplasmic, score: 9.97.
    
  0.596
ERH16637.1
Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: ahe:Arch_0747 1.9e-63 FKBP-type peptidylprolyl isomerase; K01802 peptidylprolyl isomerase; Psort location: Cytoplasmic, score: 9.67.
    
  0.596
ERH19875.1
Putative ribosomal RNA small subunit methyltransferase B; KEGG: ahe:Arch_0859 2.0e-137 Fmu (Sun) domain-containing protein; K03500 16S rRNA (cytosine967-C5)-methyltransferase; Psort location: Cytoplasmic, score: 7.50; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.546
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
   
    0.499
aspS
aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
 
    0.492
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.443
ERH19904.1
Hypothetical protein; KEGG: tpr:Tpau_4044 1.9e-113 queuine tRNA-ribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
      0.440
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.