STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH16976.1Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (325 aa)    
Predicted Functional Partners:
nrdI
nrdI protein; Probably involved in ribonucleotide reductase function.
 
 0.999
ERH16962.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
ERH16960.1
Glutaredoxin; KEGG: aai:AARI_17850 8.1e-24 nrdH; glutaredoxin electron transport component NrdH K06191.
 
  
 0.955
ERH14727.1
MaoC-like protein; KEGG: cva:CVAR_2516 0. fas; fatty acid synthase K11533; Psort location: Cytoplasmic, score: 7.50.
    
 0.946
ERH14207.1
Beta-ketoacyl synthase protein; KEGG: cva:CVAR_2516 0. fas; fatty acid synthase K11533; Psort location: CytoplasmicMembrane, score: 8.78.
    
 0.946
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.898
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.898
ERH19926.1
Nucleoside diphosphate kinase; KEGG: rdn:HMPREF0733_12074 3.0e-40 ndk; nucleoside diphosphate kinase K00940; Psort location: Cytoplasmic, score: 9.97.
     
 0.887
ERH19759.1
Pyruvate kinase; KEGG: ahe:Arch_0899 4.5e-181 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
     
 0.887
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.881
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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