STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1111 aa)    
Predicted Functional Partners:
ERH16914.1
Hypothetical protein; KEGG: sen:SACE_6661 2.4e-70 DNA-directed DNA polymerase K14161; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.977
ERH14942.1
KEGG: cfi:Celf_2369 7.8e-74 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.75.
  
 0.970
ERH16913.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
 
  
 0.968
ERH20280.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.966
ERH17674.1
Exonuclease; KEGG: ahe:Arch_1321 9.5e-69 exonuclease RNase T and DNA polymerase III; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 7.50.
  
 0.931
ERH16644.1
GIY-YIG catalytic domain protein; KEGG: cfi:Celf_2178 2.1e-142 DNA polymerase III subunit epsilon K02342; Psort location: Cytoplasmic, score: 9.97.
    
 0.864
dinB
ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.864
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.854
ERH14577.1
Hypothetical protein; KEGG: mlu:Mlut_02650 7.3e-27 DNA polymerase III, subunit gamma/tau; K02343 DNA polymerase III subunit gamma/tau; Psort location: Cytoplasmic, score: 9.97.
  
 0.854
ERH20251.1
KEGG: apb:SAR116_0400 8.5e-13 single-stranded DNA-binding protein K03111; Psort location: Cytoplasmic, score: 9.67.
  
 
 0.833
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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