STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH16698.1Glutaredoxin; Psort location: Cytoplasmic, score: 7.50. (81 aa)    
Predicted Functional Partners:
ERH16962.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.960
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.843
ERH19381.1
Thioredoxin; KEGG: cva:CVAR_2990 3.6e-37 trxA; thioredoxin; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family.
  
  
 0.713
ERH16697.1
HRDC domain protein; KEGG: bcv:Bcav_2897 4.6e-195 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
     
 0.698
ERH20264.1
KEGG: ahe:Arch_1810 4.5e-117 thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 9.97.
   
 0.616
ERH16564.1
Putative dihydrolipoyl dehydrogenase; KEGG: rcu:RCOM_0056870 4.8e-106 mercuric reductase, putative; Psort location: Cytoplasmic, score: 9.97.
  
 0.599
ERH16699.1
Hypothetical protein.
       0.572
nrdI
nrdI protein; Probably involved in ribonucleotide reductase function.
  
  
 0.541
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.405
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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