| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERH14889.1 | ERH16601.1 | HMPREF0043_02180 | HMPREF0043_01847 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | 0.843 |
| ERH14889.1 | ERH16810.1 | HMPREF0043_02180 | HMPREF0043_01695 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: ahe:Arch_1263 4.9e-175 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50. | 0.807 |
| ERH14889.1 | ERH17514.1 | HMPREF0043_02180 | HMPREF0043_01414 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.406 |
| ERH14889.1 | ERH19622.1 | HMPREF0043_02180 | HMPREF0043_00419 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 1-phosphofructokinase; KEGG: rer:RER_27710 3.2e-84 fruK; 1-phosphofructokinase K00882; Belongs to the carbohydrate kinase PfkB family. | 0.523 |
| ERH14889.1 | ERH20292.1 | HMPREF0043_02180 | HMPREF0043_00065 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | Phosphotransferase system, EIIC; KEGG: ckp:ckrop_0072 4.0e-196 bglP; beta-glucoside specific PTS system component; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 0.996 |
| ERH14889.1 | glmS | HMPREF0043_02180 | HMPREF0043_00884 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.845 |
| ERH14889.1 | pgi | HMPREF0043_02180 | HMPREF0043_01406 | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: ahe:Arch_1289 4.5e-220 glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.845 |
| ERH16601.1 | ERH14889.1 | HMPREF0043_01847 | HMPREF0043_02180 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 0.843 |
| ERH16601.1 | ERH16810.1 | HMPREF0043_01847 | HMPREF0043_01695 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | KEGG: ahe:Arch_1263 4.9e-175 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50. | 0.915 |
| ERH16601.1 | ERH17514.1 | HMPREF0043_01847 | HMPREF0043_01414 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.882 |
| ERH16601.1 | ERH19438.1 | HMPREF0043_01847 | HMPREF0043_00660 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IIB; KEGG: pfr:PFREUD_07400 4.1e-68 pmm; phosphomannomutase K07024; Psort location: Cytoplasmic, score: 7.50. | 0.849 |
| ERH16601.1 | ERH19622.1 | HMPREF0043_01847 | HMPREF0043_00419 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | 1-phosphofructokinase; KEGG: rer:RER_27710 3.2e-84 fruK; 1-phosphofructokinase K00882; Belongs to the carbohydrate kinase PfkB family. | 0.858 |
| ERH16601.1 | ERH19876.1 | HMPREF0043_01847 | HMPREF0043_00340 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | KEGG: bcv:Bcav_2050 4.1e-84 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | 0.874 |
| ERH16601.1 | ERH20292.1 | HMPREF0043_01847 | HMPREF0043_00065 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | Phosphotransferase system, EIIC; KEGG: ckp:ckrop_0072 4.0e-196 bglP; beta-glucoside specific PTS system component; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 0.962 |
| ERH16601.1 | glmS | HMPREF0043_01847 | HMPREF0043_00884 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.887 |
| ERH16601.1 | pfp | HMPREF0043_01847 | HMPREF0043_01810 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.882 |
| ERH16601.1 | pgi | HMPREF0043_01847 | HMPREF0043_01406 | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | KEGG: ahe:Arch_1289 4.5e-220 glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.919 |
| ERH16810.1 | ERH14889.1 | HMPREF0043_01695 | HMPREF0043_02180 | KEGG: ahe:Arch_1263 4.9e-175 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50. | Phosphotransferase system, EIIB; KEGG: gbr:Gbro_2915 7.7e-170 PTS system glucose subfamily transporter subunit IIA; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00. | 0.807 |
| ERH16810.1 | ERH16601.1 | HMPREF0043_01695 | HMPREF0043_01847 | KEGG: ahe:Arch_1263 4.9e-175 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50. | KEGG: ahe:Arch_1620 5.9e-108 mannose-6-phosphate isomerase K01809; Psort location: Cytoplasmic, score: 7.50. | 0.915 |
| ERH16810.1 | ERH19438.1 | HMPREF0043_01695 | HMPREF0043_00660 | KEGG: ahe:Arch_1263 4.9e-175 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IIB; KEGG: pfr:PFREUD_07400 4.1e-68 pmm; phosphomannomutase K07024; Psort location: Cytoplasmic, score: 7.50. | 0.835 |