STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERH15151.1Helicase protein; KEGG: eca:ECA1589 0. lhr; ATP-dependent helicase Lhr K03724; Psort location: Cytoplasmic, score: 7.50. (1436 aa)    
Predicted Functional Partners:
ERH19018.1
DEAD/DEAH box helicase; KEGG: adn:Alide_1118 9.0e-84 dead/h associated domain protein; K03724 ATP-dependent helicase Lhr and Lhr-like helicase; Psort location: Cytoplasmic, score: 7.50.
 
     0.976
ERH15153.1
Hypothetical protein; KEGG: ppy:PPE_04547 5.7e-08 Sirohydrochlorin cobaltochelatase (CbiXL) K03795; Psort location: Cytoplasmic, score: 7.50.
 
     0.615
ERH19700.1
Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: bcv:Bcav_2614 1.1e-56 DNA glycosylase/AP lyase; K10563 formamidopyrimidine-DNA glycosylase; Psort location: Cytoplasmic, score: 7.50; Belongs to the FPG family.
  
  
 0.552
ERH15152.1
Putative HTH-type transcriptional repressor CzrA; KEGG: apb:SAR116_2180 5.7e-07 ArsR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
       0.542
radA
Putative DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.482
ERH18967.1
uracil-DNA glycosylase, family 4; KEGG: krh:KRH_07960 1.7e-87 uracil-DNA glycosylase.
 
     0.455
ERH15336.1
Helicase protein; KEGG: hvo:HVO_1598 4.3e-09 rad25c; DNA repair helicase Rad25; Psort location: Cytoplasmic, score: 7.50.
  
 
   0.440
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.434
ERH19620.1
RNB-like protein; KEGG: mph:MLP_42770 7.4e-93 putative ribonuclease; Psort location: Cytoplasmic, score: 7.50.
  
 
   0.431
nnrD
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
 
  
 0.417
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.