STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nadKPutative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (275 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.956
ERH14388.1
Ribosomal RNA large subunit methyltransferase J; KEGG: ahe:Arch_0946 1.1e-92 hemolysin A; K06442 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.950
ERH14940.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.937
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.923
ERH14386.1
Hypothetical protein; KEGG: ase:ACPL_6362 2.3e-28 Replicase polyprotein 1ab; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.906
ERH14390.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.905
ERH14941.1
KEGG: eyy:EGYY_16240 7.2e-174 PntA; NAD/NADP transhydrogenase subunit alpha; K00324 NAD(P) transhydrogenase subunit alpha; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.897
ERH14387.1
HAD hydrolase, family IIA; KEGG: blw:W7Y_0734 6.5e-54 4-nitrophenylphosphatase; Psort location: Cytoplasmic, score: 7.50.
     
 0.872
ERH16668.1
Dihydrolipoyl dehydrogenase; KEGG: ahe:Arch_0736 2.4e-189 dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
     
 0.847
ERH14391.1
Thiaminepyrophosphokinase, catalytic domain protein; KEGG: sit:TM1040_1966 0.00010 thiamine pyrophosphokinase; K00949 thiamine pyrophosphokinase; Psort location: Cytoplasmic, score: 7.50.
       0.843
Your Current Organism:
Actinobaculum sp. F0552
NCBI taxonomy Id: 1227261
Other names: A. sp. oral taxon 183 str. F0552, Actinobaculum sp. oral taxon 183 str. F0552
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