STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERK47809.1ATPase, AAA family; KEGG: ccm:Ccan_19690 6.2e-81 Replication-associated recombination protein A K07478; Psort location: Cytoplasmic, score: 9.97. (409 aa)    
Predicted Functional Partners:
ERK52167.1
Macro domain protein; KEGG: fbr:FBFL15_1840 2.7e-48 putative bifunctional YmdB hypothetical protein/putative ADP-ribosylglycohydrolase; K05521 ADP-ribosylglycohydrolase; Psort location: Cytoplasmic, score: 8.96.
      0.728
ERK51043.1
KEGG: lba:Lebu_0805 0. DNA polymerase I; K02335 DNA polymerase I; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.546
ERK53401.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.540
ERK47808.1
Hypothetical protein; KEGG: sbh:SBI_07815 0.0017 ctaE; cytochrome c oxidase subunit III; K02276 cytochrome c oxidase subunit III; Psort location: CytoplasmicMembrane, score: 10.00.
       0.532
ERK47806.1
methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
     0.531
ERK51912.1
HRDC domain protein; KEGG: apq:APA22_12590 9.2e-11 recQ; DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ.
  
 
 0.493
ERK47412.1
KEGG: apb:SAR116_0664 1.8e-13 molybdopterin binding domain-containing protein; Psort location: Cytoplasmic, score: 8.96.
     
 0.451
dinB
ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.434
ERK51921.1
Hypothetical protein.
   
 
 0.426
ERK51910.1
HRDC domain protein; KEGG: apq:APA22_12590 2.7e-08 recQ; DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ.
   
 
 0.426
Your Current Organism:
Leptotrichia sp. F0557
NCBI taxonomy Id: 1227268
Other names: L. sp. oral taxon 879 str. F0557, Leptotrichia sp. oral taxon 879 str. F0557
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