STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ79489.1Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa)    
Predicted Functional Partners:
ERJ75741.1
KEGG: pmz:HMPREF0659_A5283 1.2e-173 lactate/malate dehydrogenase, NAD binding domain protein; K00024 malate dehydrogenase; Psort location: Cytoplasmic, score: 9.26; Belongs to the LDH/MDH superfamily.
  
 
 0.995
ERJ74779.1
KEGG: pmz:HMPREF0659_A5048 0. sdhA; succinate dehydrogenase flavoprotein subunit K00239; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.995
ERJ74777.1
KEGG: pmz:HMPREF0659_A5049 4.9e-136 succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.981
ERJ75147.1
KEGG: pmz:HMPREF0659_A6863 0. malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.977
gcvPB
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
    0.951
ERJ73602.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
    
 0.918
ERJ74780.1
Succinate dehydrogenase cytochrome B subunit, b558 family; KEGG: bhl:Bache_0807 8.7e-75 succinate dehydrogenase subunit C K00241; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.890
ERJ79638.1
FAH family protein; KEGG: rsi:Runsl_3652 3.5e-55 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; Psort location: Cytoplasmic, score: 9.97.
    
  0.878
ERJ80090.1
Pyruvate synthase; KEGG: pmz:HMPREF0659_A5561 0. nifJ; pyruvate synthase K03737.
  
 
 0.876
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.876
Your Current Organism:
Prevotella sp. F0091
NCBI taxonomy Id: 1227276
Other names: P. sp. F0091
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