STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D271_05960COG1349 Transcriptional regulators of sugar metabolism. (254 aa)    
Predicted Functional Partners:
D271_00828
PTS system fructose-specific transporter subunit IIABC; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.807
D271_00833
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.724
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.623
D271_05955
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
       0.623
D271_04639
3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
    0.596
D271_01143
3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.535
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.515
D271_04805
GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
  
 
   0.498
D271_02689
PTS system transporter subunit IIABC trhalose specific; COG2190 Phosphotransferase system IIA components.
  
  
 0.494
D271_02889
PTS system sucrose-specific transporter subunits IIBCA; COG1264 Phosphotransferase system IIB components.
  
  
 0.494
Your Current Organism:
Lactobacillus saerimneri
NCBI taxonomy Id: 1227363
Other names: L. saerimneri 30a, Lactobacillus saerimneri 30a
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.