STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D271_06095COG4479 Uncharacterized protein conserved in bacteria; Belongs to the UPF0346 family. (74 aa)    
Predicted Functional Partners:
D271_06105
GDSL-like lipase/acylhydrolase; COG2755 Lysophospholipase L1 and related esterases.
 
  
 0.947
D271_06100
COG4698 Uncharacterized protein conserved in bacteria.
 
   
 0.930
D271_06765
COG4483 Uncharacterized protein conserved in bacteria.
  
     0.724
D271_06080
23S rRNA m(5)C methyltransferase; COG0144 tRNA and rRNA cytosine-C5-methylases.
       0.682
D271_06085
Hypothetical protein.
       0.682
D271_06090
Hypothetical protein; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.
       0.682
D271_06230
Hypothetical protein; COG0457 FOG: TPR repeat.
 
     0.680
D271_06290
COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.655
D271_06670
COG1564 Thiamine pyrophosphokinase.
  
     0.640
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.634
Your Current Organism:
Lactobacillus saerimneri
NCBI taxonomy Id: 1227363
Other names: L. saerimneri 30a, Lactobacillus saerimneri 30a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.