STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D271_06335Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (371 aa)    
Predicted Functional Partners:
D271_06340
Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase.
  
 0.995
D271_06310
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.975
D271_02844
COG0720 6-pyruvoyl-tetrahydropterin synthase.
    
 0.950
D271_04744
COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase.
    
  0.949
D271_05650
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
  0.916
D271_06220
Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.
  
 
  0.916
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
    0.890
D271_00050
Ribonuclease H (); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.782
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.715
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.678
Your Current Organism:
Lactobacillus saerimneri
NCBI taxonomy Id: 1227363
Other names: L. saerimneri 30a, Lactobacillus saerimneri 30a
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