STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C450_14037COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (672 aa)    
Predicted Functional Partners:
C450_19221
COG1042 Acyl-CoA synthetase (NDP forming).
    
 0.941
C450_15605
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 
 0.918
C450_14387
2-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase.
  
 0.905
C450_12620
COG0281 Malic enzyme.
   
 0.849
C450_02715
COG0183 Acetyl-CoA acetyltransferase.
  
 
 0.779
C450_13217
COG0183 Acetyl-CoA acetyltransferase.
  
 
 0.779
C450_15118
COG0183 Acetyl-CoA acetyltransferase.
  
 
 0.779
C450_18514
Thiolase.
  
 
 0.763
C450_13442
Carbamoyl-phosphate synthase L chain ATP- binding protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 0.729
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.715
Your Current Organism:
Halococcus salifodinae
NCBI taxonomy Id: 1227456
Other names: H. salifodinae DSM 8989, Halococcus salifodinae DSM 8989
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.