STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (281 aa)    
Predicted Functional Partners:
C451_11653
COG1488 Nicotinic acid phosphoribosyltransferase.
 
 
 0.755
C451_07707
COG1056 Nicotinamide mononucleotide adenylyltransferase.
 
  
 0.740
C451_14530
CinA domain-containing protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced).
 
  
 0.730
C451_02567
Gln-dependent amino transferase; COG0367 Asparagine synthase (glutamine-hydrolyzing).
     
 0.718
C451_16725
COG0061 Predicted sugar kinase.
 
  
 0.690
nadK
Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.688
C451_09725
Isochorismatase; COG1335 Amidases related to nicotinamidase.
  
  
 0.611
C451_07027
Putative inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal type; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
    
  0.589
C451_19183
Isopentenyl-diphosphate delta isomerase; COG1524 Uncharacterized proteins of the AP superfamily.
    
  0.557
C451_01368
NUDIX hydrolase.
    
 0.532
Your Current Organism:
Halococcus thailandensis
NCBI taxonomy Id: 1227457
Other names: H. thailandensis JCM 13552, Halococcus thailandensis JCM 13552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.