STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C493_19206Cobalamin B12-binding domain-containing protein; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding). (41 aa)    
Predicted Functional Partners:
C493_07454
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 
 0.962
C493_19196
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
 
 0.942
C493_12694
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 
 0.801
C493_18256
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 
 0.801
C493_19211
LAO/AO transporter ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.
 
  
 0.689
C493_07434
methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases.
    
 0.666
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.666
C493_01836
COG1866 Phosphoenolpyruvate carboxykinase (ATP).
     
 0.646
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.643
C493_15348
2-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase.
     
 0.635
Your Current Organism:
Natronolimnobius innermongolicus
NCBI taxonomy Id: 1227499
Other names: N. innermongolicus JCM 12255, Natronolimnobius innermongolicus JCM 12255
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