STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEJ80464.13-methylfumaryl-CoA hydratase. (264 aa)    
Predicted Functional Partners:
SEJ06439.1
2-methylcitrate dehydratase PrpD.
 
    0.856
SEJ93833.1
beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.754
SEK00045.1
(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.754
SEJ35464.1
2-methylcitrate dehydratase PrpD.
  
    0.701
SEJ80485.1
Chromate reductase.
       0.644
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 
  0.639
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
  0.511
SEJ80507.1
Outer membrane protein OmpA.
       0.411
Your Current Organism:
Cribrihabitans marinus
NCBI taxonomy Id: 1227549
Other names: C. marinus, CGMCC 1.13219, Cribrihabitans marinus Chen et al. 2014, DSM 29340, JCM 19401, Phaeobacter sp. CZ-AM5, strain CZ-AM5
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