STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptaDProbable decarboxylase ptaD; Probable decarboxylase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes. The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA. As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain. The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to r [...] (138 aa)    
Predicted Functional Partners:
PFICI_07529
Uncharacterized protein.
  
 0.444
PFICI_12175
Uncharacterized protein.
  
 0.409
PFICI_11017
AMP-binding domain-containing protein.
  
 0.409
PFICI_11212
Acetyl-coenzyme A synthetase.
  
 0.409
PFICI_06300
Uncharacterized protein.
  
 0.409
PFICI_04743
Uncharacterized protein.
  
 0.409
PFICI_05876
Uncharacterized protein.
  
 0.409
PFICI_02401
AMP-binding domain-containing protein.
  
 0.409
PFICI_14790
AB hydrolase-1 domain-containing protein.
  
 
 0.401
PFICI_08381
AB hydrolase-1 domain-containing protein.
  
 
 0.401
Your Current Organism:
Pestalotiopsis fici
NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1
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