STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFICI_14090Nudix hydrolase domain-containing protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (553 aa)    
Predicted Functional Partners:
PFICI_09825
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.824
PFICI_11913
Uncharacterized protein.
    
 0.815
PFICI_08397
Tryptophan synthase.
  
  
 0.706
MDE1
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
  
 
 0.686
ADI1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
 
 0.620
PFICI_04197
Hcy-binding domain-containing protein.
   
  
 0.620
PFICI_06457
Uncharacterized protein.
  
 
 0.590
PFICI_04261
Uncharacterized protein.
  
 
 0.590
PFICI_14172
Homoserine dehydrogenase.
  
  
 0.539
PFICI_06365
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
  
 0.526
Your Current Organism:
Pestalotiopsis fici
NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.