STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFICI_135243-hydroxy-3-methylglutaryl coenzyme A reductase. (1155 aa)    
Predicted Functional Partners:
PFICI_14651
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.996
PFICI_14097
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.996
PFICI_12068
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.992
PFICI_04283
Uncharacterized protein.
   
  
 0.932
PFICI_11539
Uncharacterized protein.
   
 
 0.894
PFICI_07568
RING-type domain-containing protein.
   
 
 0.867
PFICI_04845
Isopentenyl-diphosphate Delta-isomerase.
 
  
 0.814
PFICI_07631
Uncharacterized protein.
   
 
 0.778
PFICI_03589
Eburicol 14-alpha-demethylase; Belongs to the cytochrome P450 family.
  
  
 0.772
PFICI_01425
Eburicol 14-alpha-demethylase; Belongs to the cytochrome P450 family.
  
  
 0.772
Your Current Organism:
Pestalotiopsis fici
NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1
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