STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFICI_05012Uncharacterized protein. (533 aa)    
Predicted Functional Partners:
PFICI_00891
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.910
PFICI_04679
ATP-dependent DNA helicase II subunit 1.
     
 0.775
PFICI_14132
ERCC4 domain-containing protein.
   
 
 0.767
PFICI_01384
BRCT domain-containing protein.
    
 
 0.766
PFICI_04985
Uncharacterized protein.
 
      0.754
PFICI_02897
Endo/exonuclease/phosphatase domain-containing protein.
   
 
 0.744
PFICI_14546
DNA ligase.
   
 
 0.700
PFICI_01386
ERCC4 domain-containing protein.
   
 
 0.700
PFICI_07637
zf-C2HE domain-containing protein.
    
 
 0.697
PFICI_08850
Uncharacterized protein.
    
 
 0.689
Your Current Organism:
Pestalotiopsis fici
NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1
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