STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APX22843.1Histidine triad (HIT) family protein; PFAM: HIT domain. (122 aa)    
Predicted Functional Partners:
APX22844.1
Putative N-acetylglucosaminyltransferase; PFAM: Core-2/I-Branching enzyme.
  
   0.861
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.741
APX22845.1
PFAM: Sulfotransferase family.
       0.704
APX25496.1
PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 
  0.680
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
  0.645
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.644
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.632
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
   
 0.530
APX23476.1
PFAM: Trm112p-like protein; Belongs to the UPF0434 family.
  
    0.445
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
 
 0.444
Your Current Organism:
Salipiger profundus
NCBI taxonomy Id: 1229727
Other names: CGMCC 1.12377, DSM 27508 [[Salipiger nanhaiensis]], Donghicola sp. ZH114, JCM 19383 [[Salipiger nanhaiensis]], KCTC 32468 [[Salipiger nanhaiensis]], LMG 27365, LMG:27365, S. profundus, Salipiger nanhaiensis, Salipiger nanhaiensis Dai et al. 2015, Salipiger sp. JLT2016, Thiobacimonas profunda, Thiobacimonas profunda Li et al. 2015 emend. Huang et al. 2017, strain JLT2016, strain ZH114 [[Salipiger nanhaiensis]]
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